3-Methyl-1-phenyl-4-[(phen­yl)(2-phenyl­hydrazin-1-yl)meth­ylidene]-1H-pyrazol-5(4H)-one

نویسندگان

  • Omoruyi G. Idemudia
  • Alexander P. Sadimenko
  • Anthony J. Afolayan
  • Eric C. Hosten
چکیده

The title compound, C(23)H(20)N(4)O, is a heterocyclic phenyl-hydrazone Schiff base with a pyrazole moiety. In the crystal, a variety of inter-actions occur, including N-H⋯π and π-π stacking between the phenyl ring of the phenyl-hydrazinyl group and its symmetry-generated equivalent [centroid-centroid distance = 3.6512 (7) Å].

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منابع مشابه

(4Z)-4-[(4-Chloro­anilino)(phen­yl)methyl­ene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one

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3-Methyl-1-phenyl-4-[(Z)-phen­yl(4-acetamido­anilino)methyl­idene]-1H-pyrazol-5(4H)-one

In the title compound, C(25)H(22)N(4)O(2), the dihedral angles between the central pyrazole ring and the phenyl and benzene rings are 37.01 (3), 75.58 (7) and 49.67 (8)°. An intra-molecular N-H⋯O hydrogen bond generates an S(6) motif. In the crystal, N-H⋯O hydrogen bonds link mol-ecules into a zigzag chain extended along the b axis.

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Synthesis Characterization and Biological Evaluation of Novel Thiazole Derivatives Containing Indole Moiety Bearing-Tetrazole

Purpose: The article is aimed to synthesize,characterize and screening the biological activity of a series of Synthesis of 1-(2-(3-(3-chloro-1-(4-substituted phenyl)-4-tetrazole-2-yl)-1H-indol-1-yl)acetyl)-4-(2-(4substituted phenyl)hydrazono)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one 4(a-f). Indole-3-carbaldehyde and chloro ethyl acetate were dissolved in DMF. To this reaction mixture anhydrous ...

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عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2012